Compounded Sterile Medications

Compounding sterile medications is no joke. It involves Risk Level III compounding, the highest risk for sterile medications available. This holds true for:

Eye drops: Vancomycin, tobramycin, ceftazidime and albumin

Intracavernosal injections: Tri-Mix (Papaverine/ Phentolamine/Alprostadil)

Inhalation medications: Calcium gluconate nebulizers

IM injections: Dexamethasone acetate, methylcobalamin and glutathione

Subcutaneous injections: hCG

IV medications: Myer's cocktails and Thyroid Releasing Hormone (TRH)

ACCREDITED:

The Pharmacy Compounding Accreditation Board (PCAB) accreditation is the highest attainable accreditation in compounding pharmacy. Make no mistake, they are the highest standards in the nation and the most difficult to achieve. Compounding Corner Pharmacy is the ONLY PCAB-Accredited pharmacy for sterile and non-sterile compounding in Fort Bend County.

ENDORSED:


United States Pharmacopeia (USP) <795> and <797> are the actual standards that compounding pharmacies are held to. PCAB is endorsed by USP, the American Medical Association (AMA) and more than a dozen other organizations.

PROCESS VALIDATED:

How do you know it's really in there? The FDA allows manufacturers a +/- 20% error (There are several narrow therapeutic index exceptions ). USP allows compounding pharmacies a +/-  10% error. We'll let our potency testing speak for itself

MEDICATION REPORTED MEASURED POTENCY
Demecarium Bromide Eye Drops 0.125% 0.133% 106%
Dexamethasone Acetate 16mg/mL 16.9mg/mL 106%
Dexamethasone Acetate 16mg/mL 16.6mg/mL 104%
Dexamethasone Acetate 16mg/mL 15.2mg/mL 95%
Dexamethasone Acetate 16mg/mL 16.87mg/mL 105.4%
Dexamethasone Acetate 16mg/mL 16.018mg/mL 100.11%
Glutathione-Reduced 100mg/mL 102mg/mL 102%
Glutathione-Reduced 100mg/mL 92.9mg/mL 92.9%
Methylcobalamin 25mg/mL 23.67mg/mL 94.7%
Methylcobalamin 25mg/mL 22.7mg/mL 90.8%
Protireln (TRH) 0.5mg/mL 0.517mg/mL 103.3%
Protirelin (TRH) 0.5mg/mL 0.504mg/mL 100.8 %
Protirelin (TRH) 0.5mg/mL 0.52mg/mL 103.4%
Protirelin (TRH) 0.5mg/mL 0.51mg/mL 101.5%
Protirelin (TRH) 0.5mg/mL 0.52mg/mL 104.4%
Protirelin (TRH) 0.5mg/mL 0.53mg/mL 106.2%
Protirelin (TRH) 0.5mg/mL 0.516mg/mL 103.1%
Protirelin (TRH) 0.5mg/mL 0.483mg/mL 96.6%
Protirelin (TRH) 0.5mg/mL 0.523mg/ml 105%
Tri-Mix (Papaverine) 30mg/mL 30.8mg/mL 102.6%
Tri-Mix (Phentolamine) 1mg/mL 1.00mg/mL 100.0%
Tri-Mix (Alprostadil) 10mcg/mL 9.33mcg/mL 93.3%

 USP <797> states: "...compound preparations are to be prepared to ensure that each preparation shall contain not less than 90% and not more than 110% of the theoretically calculated and labeled quantity of an active ingredient...". Potency determinations follow USP <621> HPLC, USP <851> Spectophotometry, and specific monograph testing procedures. 

Compounding Corner Pharmacy is accredited by PCAB which is endorsed by:

  • The American Medical Association
  • The United States Pharmacopeia
  • The National Association of Boards of Pharmacy
  • The International Academy of Compounding Pharmacies
  • The American Pharmacists Association
  • The American College of Apothecaries
  • The National Community Pharmacists Association
  • The National Alliance of State Pharmacy Associations
  • The National Home Infusion Association
  • The American Veterinary Medical Association
  • The American Animal Hospital Association